BLOOD PRESSURE SUPPORT

Blood pressure homeostasis is a clear indication of health. Approximately 9 million deaths due to high blood pressure occur each year. (16) This makes essential hypertension the most prominent disease worldwide. Uncontrolled blood pressure increases the risk for heart-related problems such as stroke, coronary artery disease, and heart failure. When left untreated, high blood pressure may lead to chronic kidney disease, disability, and even death. (4)

Interventions aimed at lowering blood pressure improve comorbidities and outcomes. Patients with uncomplicated grade 1 hypertension experience decreased risk of stroke and death when lowering blood pressure by an average of 3.6 mmHg systolic, and 2.4 mmHg diastolic. (23) Targeting reductions in blood pressure, as well as underlying mechanisms, is key to an integrative treatment plan.

Based on current research findings presented below, the ingredients in this protocol have demonstrated efficacy in improving blood pressure profile.

Support your treatment plan with this blood pressure handout for patients.

Magnesium

300-450 mg of elemental magnesium, total per day, 1 to 6 months (5)(26)

• An inverse correlation between levels of circulating magnesium and the incidence of hypertension has been clearly identified (12)
• Meta-analysis of three trials (14,876 participants, 6.7 year follow up) found that every 0.1 mmol/L incremental increase in circulating Mg levels was associated with 4% (RR, 0.96; 95% CI: 0.94, 0.99) reduction in hypertension incidence (25) 
• Patients with insulin resistance, prediabetes, and other chronic noncommunicable diseases supplemented with 365 to 450 mg per day of magnesium had an overall decrease in blood pressure with a mean reduction in systolic by 4.18 mmHg and diastolic by 2.27 mmHg (5)
• Supplementation with a median dose of 368 mg per day of magnesium for a median duration of three months increased serum magnesium by 0.05 mmol/L and resulted in decreasing systolic blood pressure by 2.0 mmHg and diastolic blood pressure by 1.78 mmHg (26)
• Supplementation with magnesium decrease systolic and diastolic blood pressure by 3-4 mm Hg and 2-3 mm Hg respectively across trials with a range of 120-973 mg per day supplementation for 3-24 weeks; supplementation with more than 370 mg per day demonstrated an increased effect size (14)

Garlic